Just got my pair in today. Quick warmup and listen (Fio X-3 -> Digital out to Neko D-100 Mk 2 -> Eddie Current Lunchbox 2) using some 16/44 up to 24/192 FLAC files.
First impressions: big and full sounding, fairly well balanced with maybe some lightness to bass (assume it may get better in time). It actually reminded me of many of the good things about Grado's, with a little larger soundstage and a little more evenly balanced. Not as wide open as my Senn 600's coming out of the Lunchbox 2, but still pretty good for a closed phone.
Isolation was good, I think these will do quite well at work. Got some good details/transparency out of them, too, thanks likely to the DAC. Comfort was good, not too strong of a clamp, and the insides of the cups didn't rub on my ears (thought they might given their size). Probably not as comfy as the Phillips Fidelio X1's, which have larger, felt earpads.
Will compare them at work tomorrow, fed from same FLAC files to the Meridian Explorer, to the X1's I had been using.
As a side note: I like this Fio X3 DAP a lot. Some/several things NOT to like, but they matter less to me (menu system especially, and some reported bugs reading LOTS of files - I put exclusively FLAC on with lots of hi-rez, so no worries about filesystem for me). Sound out to the Ety 4P's is very good, and using it as a digital source is simple and real nice. I listen to the above setup with the Neko and EC feeding my Senn 600's almost every other night, and it is quite fun.